Micar21 Ltd. provides broad range of consulting services, including but not limited to:
Changes in the ligand binding affinity and selectivity introduced by point mutations.
Our team has a solid experience and have already assisted several scientific projects during the study of a concrete residue mutations that affect ligand binding and selectivity to concrete receptor. We provide not only an estimate about the free energy changes but also the structural and dynamical impact of any specified mutation. This is in a great help to many experimental groups, can speed up their projects and safe significant amount of the budget!
In addition to above mentioned areas we provide also consultations for large number of services that relate to the computational chemistry and biology. Don't hesitate to contact us!